Involvement of Ca(2+)-activated K(+) channel 3.1 in hypoxia-induced pulmonary arterial hypertension and therapeutic effects of TRAM-34 in rats

Pulmonary artery hypertension (PAH) is an incurable disease associated with the proliferation of pulmonary artery smooth muscle cells (PASMCs) and vascular remodeling. The present study examined whether TRAM-34, a highly selective blocker of calcium-activated potassium channel 3.1 (Kca3.1), can help...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Shujin, Shen, Yongchun, He, Guangming, Wang, Tao, Xu, Dan, Wen, Fuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529208/
https://www.ncbi.nlm.nih.gov/pubmed/28679649
http://dx.doi.org/10.1042/BSR20170763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529208/
https://www.ncbi.nlm.nih.gov/pubmed/28679649
http://dx.doi.org/10.1042/BSR20170763

Ejemplares similares