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Involvement of Ca(2+)-activated K(+) channel 3.1 in hypoxia-induced pulmonary arterial hypertension and therapeutic effects of TRAM-34 in rats

Pulmonary artery hypertension (PAH) is an incurable disease associated with the proliferation of pulmonary artery smooth muscle cells (PASMCs) and vascular remodeling. The present study examined whether TRAM-34, a highly selective blocker of calcium-activated potassium channel 3.1 (Kca3.1), can help...

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Detalles Bibliográficos
Autores principales:	Guo, Shujin, Shen, Yongchun, He, Guangming, Wang, Tao, Xu, Dan, Wen, Fuqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529208/ https://www.ncbi.nlm.nih.gov/pubmed/28679649 http://dx.doi.org/10.1042/BSR20170763

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