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Sub-microscopic analysis of t-tubule geometry in living cardiac ventricular myocytes using a shape-based analysis method

Transverse-axial tubules (TTs) are key structures involved in cardiac excitation-contraction coupling and can become deranged in disease. Although optical measurement of TTs is frequently employed to assess TT abundance and regularity, TT dimensions are generally below the diffraction limit of optic...

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Detalles Bibliográficos
Autores principales: Kong, Cherrie H.T., Rog-Zielinska, Eva A., Orchard, Clive H., Kohl, Peter, Cannell, Mark B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529290/
https://www.ncbi.nlm.nih.gov/pubmed/28483597
http://dx.doi.org/10.1016/j.yjmcc.2017.05.003