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A high-content image analysis approach for quantitative measurements of chemosensitivity in patient-derived tumor microtissues
Organotypic, three-dimensional (3D) cancer models have enabled investigations of complex microtissues in increasingly realistic conditions. However, a drawback of these advanced models remains the poor biological relevance of cancer cell lines, while higher clinical significance would be obtainable...
Autores principales: | Ahonen, Ilmari, Åkerfelt, Malin, Toriseva, Mervi, Oswald, Eva, Schüler, Julia, Nees, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529420/ https://www.ncbi.nlm.nih.gov/pubmed/28747710 http://dx.doi.org/10.1038/s41598-017-06544-x |
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