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A high-content image analysis approach for quantitative measurements of chemosensitivity in patient-derived tumor microtissues

Organotypic, three-dimensional (3D) cancer models have enabled investigations of complex microtissues in increasingly realistic conditions. However, a drawback of these advanced models remains the poor biological relevance of cancer cell lines, while higher clinical significance would be obtainable...

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Detalles Bibliográficos
Autores principales: Ahonen, Ilmari, Åkerfelt, Malin, Toriseva, Mervi, Oswald, Eva, Schüler, Julia, Nees, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529420/
https://www.ncbi.nlm.nih.gov/pubmed/28747710
http://dx.doi.org/10.1038/s41598-017-06544-x