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Reducing Animal Use with a Biotelemetry-Enhanced Murine Model of Sepsis

Animal models of sepsis exhibit considerable variability in the temporal development of the physiologic response, which reduces the power of studies, particularly if interventions are tested at arbitrary time points. We developed a biotelemetry-based model of cecal ligation and puncture (CLP) that s...

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Detalles Bibliográficos
Autores principales: Lewis, Anthony, Zuckerbraun, Brian, Griepentrog, John, Zhang, Xianghong, Rosengart, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529427/
https://www.ncbi.nlm.nih.gov/pubmed/28747734
http://dx.doi.org/10.1038/s41598-017-05497-5