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Reducing Animal Use with a Biotelemetry-Enhanced Murine Model of Sepsis
Animal models of sepsis exhibit considerable variability in the temporal development of the physiologic response, which reduces the power of studies, particularly if interventions are tested at arbitrary time points. We developed a biotelemetry-based model of cecal ligation and puncture (CLP) that s...
Autores principales: | Lewis, Anthony, Zuckerbraun, Brian, Griepentrog, John, Zhang, Xianghong, Rosengart, Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529427/ https://www.ncbi.nlm.nih.gov/pubmed/28747734 http://dx.doi.org/10.1038/s41598-017-05497-5 |
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