Cargando…
Porcine familial adenomatous polyposis model enables systematic analysis of early events in adenoma progression
We compared gene expression in low and high-grade intraepithelial dysplastic polyps from pigs carrying an APC (1311) truncating mutation orthologous to human APC (1309), analysing whole samples and microdissected dysplastic epithelium. Gene set enrichment analysis revealed differential expression of...
Autores principales: | , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529429/ https://www.ncbi.nlm.nih.gov/pubmed/28747659 http://dx.doi.org/10.1038/s41598-017-06741-8 |