Cargando…
Porcine familial adenomatous polyposis model enables systematic analysis of early events in adenoma progression
We compared gene expression in low and high-grade intraepithelial dysplastic polyps from pigs carrying an APC (1311) truncating mutation orthologous to human APC (1309), analysing whole samples and microdissected dysplastic epithelium. Gene set enrichment analysis revealed differential expression of...
Autores principales: | Flisikowska, Tatiana, Stachowiak, Monika, Xu, Hongen, Wagner, Alexandra, Hernandez-Caceres, Alejandra, Wurmser, Christine, Perleberg, Carolin, Pausch, Hubert, Perkowska, Anna, Fischer, Konrad, Frishman, Dmitrij, Fries, Ruedi, Switonski, Marek, Kind, Alexander, Saur, Dieter, Schnieke, Angelika, Flisikowski, Krzysztof |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529429/ https://www.ncbi.nlm.nih.gov/pubmed/28747659 http://dx.doi.org/10.1038/s41598-017-06741-8 |
Ejemplares similares
-
Altered microRNA profiles during early colon adenoma progression in a porcine model of familial adenomatous polyposis
por: Stachowiak, Monika, et al.
Publicado: (2017) -
Wild-type APC Influences the Severity of Familial Adenomatous Polyposis
por: Flisikowski, Krzysztof, et al.
Publicado: (2021) -
In frame exon skipping in UBE3B is associated with developmental disorders and increased mortality in cattle
por: Venhoranta, Heli, et al.
Publicado: (2014) -
Homozygous haplotype deficiency reveals deleterious mutations compromising reproductive and rearing success in cattle
por: Pausch, Hubert, et al.
Publicado: (2015) -
A frameshift mutation in GON4L is associated with proportionate dwarfism in Fleckvieh cattle
por: Schwarzenbacher, Hermann, et al.
Publicado: (2016)