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Porcine familial adenomatous polyposis model enables systematic analysis of early events in adenoma progression

We compared gene expression in low and high-grade intraepithelial dysplastic polyps from pigs carrying an APC (1311) truncating mutation orthologous to human APC (1309), analysing whole samples and microdissected dysplastic epithelium. Gene set enrichment analysis revealed differential expression of...

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Detalles Bibliográficos
Autores principales: Flisikowska, Tatiana, Stachowiak, Monika, Xu, Hongen, Wagner, Alexandra, Hernandez-Caceres, Alejandra, Wurmser, Christine, Perleberg, Carolin, Pausch, Hubert, Perkowska, Anna, Fischer, Konrad, Frishman, Dmitrij, Fries, Ruedi, Switonski, Marek, Kind, Alexander, Saur, Dieter, Schnieke, Angelika, Flisikowski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529429/
https://www.ncbi.nlm.nih.gov/pubmed/28747659
http://dx.doi.org/10.1038/s41598-017-06741-8

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