A single amino acid substitution confers B-cell clonogenic activity to the HIV-1 matrix protein p17

Recent data highlight the presence, in HIV-1-seropositive patients with lymphoma, of p17 variants (vp17s) endowed with B-cell clonogenicity, suggesting a role of vp17s in lymphomagenesis. We investigated the mechanisms responsible for the functional disparity on B cells between a wild-type p17 (refp...

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Detalles Bibliográficos
Autores principales: Giagulli, Cinzia, D’Ursi, Pasqualina, He, Wangxiao, Zorzan, Simone, Caccuri, Francesca, Varney, Kristen, Orro, Alessandro, Marsico, Stefania, Otjacques, Benoît, Laudanna, Carlo, Milanesi, Luciano, Dolcetti, Riccardo, Fiorentini, Simona, Lu, Wuyuan, Caruso, Arnaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529431/
https://www.ncbi.nlm.nih.gov/pubmed/28747658
http://dx.doi.org/10.1038/s41598-017-06848-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529431/
https://www.ncbi.nlm.nih.gov/pubmed/28747658
http://dx.doi.org/10.1038/s41598-017-06848-y

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