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A single amino acid substitution confers B-cell clonogenic activity to the HIV-1 matrix protein p17
Recent data highlight the presence, in HIV-1-seropositive patients with lymphoma, of p17 variants (vp17s) endowed with B-cell clonogenicity, suggesting a role of vp17s in lymphomagenesis. We investigated the mechanisms responsible for the functional disparity on B cells between a wild-type p17 (refp...
Autores principales: | Giagulli, Cinzia, D’Ursi, Pasqualina, He, Wangxiao, Zorzan, Simone, Caccuri, Francesca, Varney, Kristen, Orro, Alessandro, Marsico, Stefania, Otjacques, Benoît, Laudanna, Carlo, Milanesi, Luciano, Dolcetti, Riccardo, Fiorentini, Simona, Lu, Wuyuan, Caruso, Arnaldo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529431/ https://www.ncbi.nlm.nih.gov/pubmed/28747658 http://dx.doi.org/10.1038/s41598-017-06848-y |
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