Bone matrix components activate the NLRP3 inflammasome and promote osteoclast differentiation

The NLRP3 inflammasome senses a variety of signals referred to as danger associated molecular patterns (DAMPs), including those triggered by crystalline particulates or degradation products of extracellular matrix. Since some DAMPs confer tissue-specific activation of the inflammasomes, we tested th...

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Detalles Bibliográficos
Autores principales: Alippe, Yael, Wang, Chun, Ricci, Biancamaria, Xiao, Jianqiu, Qu, Chao, Zou, Wei, Novack, Deborah V., Abu-Amer, Yousef, Civitelli, Roberto, Mbalaviele, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529467/
https://www.ncbi.nlm.nih.gov/pubmed/28747793
http://dx.doi.org/10.1038/s41598-017-07014-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529467/
https://www.ncbi.nlm.nih.gov/pubmed/28747793
http://dx.doi.org/10.1038/s41598-017-07014-0

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