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Echinomycin inhibits adipogenesis in 3T3-L1 cells in a HIF-independent manner

Obesity is a risk factor for many diseases including diabetes, cancer, cardiovascular disease, and chronic kidney disease. Obesity is characterized by the expansion of white adipose tissue (WAT). Hypertrophy and hyperplasia of adipocytes cause tissue hypoxia followed by inflammation and fibrosis. It...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Junna, Tanaka, Tetsuhiro, Saito, Hisako, Nomura, Seitaro, Aburatani, Hiroyuki, Waki, Hironori, Kadowaki, Takashi, Nangaku, Masaomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529514/
https://www.ncbi.nlm.nih.gov/pubmed/28747725
http://dx.doi.org/10.1038/s41598-017-06761-4