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Engineering the geometrical shape of mesenchymal stromal cells through defined cyclic stretch regimens

Stem cells have been predicted to improve disease outcomes and patient lives. Steering stem cell fate - through controlling cell shape - may substantially accelerate progress towards this goal. As mesenchymal stromal cells (MSCs) are continuously exposed in vivo to a dynamically changing biomechanic...

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Detalles Bibliográficos
Autores principales: Walters, Brandan, Uynuk-Ool, Tatiana, Rothdiener, Miriam, Palm, Julian, Hart, Melanie L., Stegemann, Jan P., Rolauffs, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529555/
https://www.ncbi.nlm.nih.gov/pubmed/28747783
http://dx.doi.org/10.1038/s41598-017-06794-9