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Engineering the geometrical shape of mesenchymal stromal cells through defined cyclic stretch regimens
Stem cells have been predicted to improve disease outcomes and patient lives. Steering stem cell fate - through controlling cell shape - may substantially accelerate progress towards this goal. As mesenchymal stromal cells (MSCs) are continuously exposed in vivo to a dynamically changing biomechanic...
Autores principales: | Walters, Brandan, Uynuk-Ool, Tatiana, Rothdiener, Miriam, Palm, Julian, Hart, Melanie L., Stegemann, Jan P., Rolauffs, Bernd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529555/ https://www.ncbi.nlm.nih.gov/pubmed/28747783 http://dx.doi.org/10.1038/s41598-017-06794-9 |
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