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Overcoming blood brain barrier with a dual purpose Temozolomide loaded Lactoferrin nanoparticles for combating glioma (SERP-17-12433)

Targeted delivery of drugs to the brain is challenging due to the restricted permeability across the blood brain barrier (BBB). Gliomas are devastating cancers and their positive treatment outcome using Temozolomide (TMZ) is limited due to its short plasma half-life, systemic toxicity and limited ac...

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Detalles Bibliográficos
Autores principales: Kumari, Sonali, Ahsan, Saad M., Kumar, Jerald M., Kondapi, Anand K., Rao, Nalam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529576/
https://www.ncbi.nlm.nih.gov/pubmed/28747713
http://dx.doi.org/10.1038/s41598-017-06888-4