Slow conformational exchange and overall rocking motion in ubiquitin protein crystals

Proteins perform their functions in solution but their structures are most frequently studied inside crystals. Here we probe how the crystal packing alters microsecond dynamics, using solid-state NMR measurements and multi-microsecond MD simulations of different crystal forms of ubiquitin. In partic...

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Detalles Bibliográficos
Autores principales: Kurauskas, Vilius, Izmailov, Sergei A., Rogacheva, Olga N., Hessel, Audrey, Ayala, Isabel, Woodhouse, Joyce, Shilova, Anastasya, Xue, Yi, Yuwen, Tairan, Coquelle, Nicolas, Colletier, Jacques-Philippe, Skrynnikov, Nikolai R., Schanda, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529581/
https://www.ncbi.nlm.nih.gov/pubmed/28747759
http://dx.doi.org/10.1038/s41467-017-00165-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529581/
https://www.ncbi.nlm.nih.gov/pubmed/28747759
http://dx.doi.org/10.1038/s41467-017-00165-8

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