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TGFβ-induced osteogenic potential of human amniotic fluid stem cells via CD73-generated adenosine production

The human amniotic fluid stem cell (hAFSC) population consists of two morphologically distinct subtypes, spindle-shaped and round-shaped cells (SS-hAFSCs and RS-hAFSCs). Whilst SS-hAFSCs are routinely expanded in mesenchymal-type (MT) conditions, we previously showed that they acquire broader differ...

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Detalles Bibliográficos
Autores principales: Hau, Kwan-Leong, Ranzoni, Anna Maria, Vlahova, Filipa, Hawkins, Kate, De Coppi, Paolo, David, Anna L., Guillot, Pascale V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529586/
https://www.ncbi.nlm.nih.gov/pubmed/28747757
http://dx.doi.org/10.1038/s41598-017-06780-1