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NADPH Oxidase 2 Regulates NLRP3 Inflammasome Activation in the Brain after Traumatic Brain Injury

Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. After the initial primary mechanical injury, a complex secondary injury cascade involving oxidative stress and neuroinflammation follows, which may exacerbate the injury and complicate the healing process. NADPH oxida...

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Detalles Bibliográficos
Autores principales: Ma, Merry W., Wang, Jing, Dhandapani, Krishnan M., Brann, Darrell W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529650/
https://www.ncbi.nlm.nih.gov/pubmed/28785377
http://dx.doi.org/10.1155/2017/6057609