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Ginkgolide B Suppresses TLR4-Mediated Inflammatory Response by Inhibiting the Phosphorylation of JAK2/STAT3 and p38 MAPK in High Glucose-Treated HUVECs

AIM: Ginkgolide B is a Ginkgo biloba leaf extract that has been identified as a natural platelet-activating factor receptor (PAFR) antagonist. We investigated the effect of ginkgolide B on high glucose-induced TLR4 activation in human umbilical vein endothelial cells (HUVECs). METHODS: Protein expre...

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Detalles Bibliográficos
Autores principales: Chen, Kun, Sun, Wenjia, Jiang, Yun, Chen, Beidong, Zhao, Yanyang, Sun, Jie, Gong, Huan, Qi, Ruomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529656/
https://www.ncbi.nlm.nih.gov/pubmed/28785380
http://dx.doi.org/10.1155/2017/9371602