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Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1

Human coronavirus (CoV) HKU1 is a pathogen causing acute respiratory illnesses and so far little is known about its biology. HKU1 virus uses its S1 subunit C-terminal domain (CTD) and not the N-terminal domain like other lineage A β-CoVs to bind to its yet unknown human receptor. Here we present the...

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Detalles Bibliográficos
Autores principales: Ou, Xiuyuan, Guan, Hongxin, Qin, Bo, Mu, Zhixia, Wojdyla, Justyna A., Wang, Meitian, Dominguez, Samuel R., Qian, Zhaohui, Cui, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529671/
https://www.ncbi.nlm.nih.gov/pubmed/28534504
http://dx.doi.org/10.1038/ncomms15216