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Development of an automated in vitro selection protocol to obtain RNA-based aptamers: identification of a biostable substance P antagonist
We have developed an automated SELEX (Systematic Evolution of Ligands by EXponential Enrichment) process that allows the execution of in vitro selection cycles without any direct manual intervention steps. The automated selection protocol is designed to provide for high flexibility and versatility i...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC552970/ https://www.ncbi.nlm.nih.gov/pubmed/15745995 http://dx.doi.org/10.1093/nar/gni044 |