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Development of an automated in vitro selection protocol to obtain RNA-based aptamers: identification of a biostable substance P antagonist

We have developed an automated SELEX (Systematic Evolution of Ligands by EXponential Enrichment) process that allows the execution of in vitro selection cycles without any direct manual intervention steps. The automated selection protocol is designed to provide for high flexibility and versatility i...

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Detalles Bibliográficos
Autores principales: Eulberg, Dirk, Buchner, Klaus, Maasch, Christian, Klussmann, Sven
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC552970/
https://www.ncbi.nlm.nih.gov/pubmed/15745995
http://dx.doi.org/10.1093/nar/gni044