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Pharmacometric Modeling of Liver Metastases' Diameter, Volume, and Density and Their Relation to Clinical Outcome in Imatinib‐Treated Patients With Gastrointestinal Stromal Tumors

Three‐dimensional and density‐based tumor metrics have been suggested to better discriminate tumor response to treatment than unidimensional metrics, particularly for tumors exhibiting nonuniform size changes. In the developed pharmacometric modeling framework based on data from 77 imatinib‐treated...

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Detalles Bibliográficos
Autores principales: Schindler, E, Krishnan, SM, Mathijssen, RHJ, Ruggiero, A, Schiavon, G, Friberg, LE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529749/
https://www.ncbi.nlm.nih.gov/pubmed/28379635
http://dx.doi.org/10.1002/psp4.12195