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Dissociated Agonist of Glucocorticoid Receptor or Prednisone for Active Rheumatoid Arthritis: Effects on P1NP and Osteocalcin Pharmacodynamics

Fosdagrocorat (PF‐04171327), a dissociated agonist of the glucocorticoid receptor, has potent anti‐inflammatory activity in patients with rheumatoid arthritis with reduced adverse effects on bone health. To identify fosdagrocorat doses with bone formation marker changes similar to prednisone 5 mg, w...

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Detalles Bibliográficos
Autores principales: Shoji, S, Suzuki, A, Conrado, DJ, Peterson, MC, Hey‐Hadavi, J, McCabe, D, Rojo, R, Tammara, BK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529777/
https://www.ncbi.nlm.nih.gov/pubmed/28556506
http://dx.doi.org/10.1002/psp4.12201