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Dissociated Agonist of Glucocorticoid Receptor or Prednisone for Active Rheumatoid Arthritis: Effects on P1NP and Osteocalcin Pharmacodynamics
Fosdagrocorat (PF‐04171327), a dissociated agonist of the glucocorticoid receptor, has potent anti‐inflammatory activity in patients with rheumatoid arthritis with reduced adverse effects on bone health. To identify fosdagrocorat doses with bone formation marker changes similar to prednisone 5 mg, w...
Autores principales: | Shoji, S, Suzuki, A, Conrado, DJ, Peterson, MC, Hey‐Hadavi, J, McCabe, D, Rojo, R, Tammara, BK |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529777/ https://www.ncbi.nlm.nih.gov/pubmed/28556506 http://dx.doi.org/10.1002/psp4.12201 |
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