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Poly (ADP-ribose) polymerase-1 inhibition decreases proliferation through G2/M arrest in esophageal squamous cell carcinoma

Poly (ADP-ribose) polymerase-1 (PARP1) plays a vital role in DNA repair and is expected to be an effective target in various malignancies. The aim of the present study was to investigate the clinical and biological significance of PARP1 expression in esophageal squamous cell carcinoma (ESCC). Immuno...

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Detalles Bibliográficos
Autores principales: Yamamoto, Masaaki, Yamasaki, Makoto, Tsukao, Yukiko, Tanaka, Koji, Miyazaki, Yasuhiro, Makino, Tomoki, Takahashi, Tsuyoshi, Kurokawa, Yukinori, Nakajima, Kiyokazu, Takiguchi, Shuji, Mori, Masaki, Doki, Yuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529935/
https://www.ncbi.nlm.nih.gov/pubmed/28789382
http://dx.doi.org/10.3892/ol.2017.6334