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Characterization of the aminopyridine derivative KRC-180 as a JAK2 inhibitor

Janus kinase 2 (JAK2) is a non-receptor tyrosine kinase that regulates the signal transducer and activator of transcription (STAT) signaling pathway. Deregulation of JAK2 signaling has previously been observed in hematologic malignancies, including erythroleukemia. In the present study, an aminopyri...

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Detalles Bibliográficos
Autores principales: Yoon, Kyoung Bin, Cho, Sung Yun, An, Su Jin, Park, Kyeong Ryang, Lee, Hyo Jeong, Yoon, Hae Sung, Lee, Sun-Mi, Kim, Yong-Chul, Han, Sun-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529941/
https://www.ncbi.nlm.nih.gov/pubmed/28789350
http://dx.doi.org/10.3892/ol.2017.6353