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p53 performs an essential role in mediating the oncogenic stimulus triggered by loss of expression of neurofibromatosis type 2 during in vitro tumor progression

The loss of the tumor suppressor neurofibromatosis type 2 gene, encoding merlin, has been considered to be a fundamental event during the malignant progression of various cell types. However, a consensus for the mainstream mechanism, by which merlin deficiency contributes to uncontrolled cellular pr...

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Detalles Bibliográficos
Autores principales: Li, Xiye, Chen, Hongsai, Xue, Lu, Pang, Xiuhong, Zhang, Xiaoman, Zhu, Zhengjie, Zhu, Weidong, Wang, Zhaoyan, Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530008/
https://www.ncbi.nlm.nih.gov/pubmed/28789444
http://dx.doi.org/10.3892/ol.2017.6445