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Suppression of p53 potentiates chemosensitivity in nutrient-deprived cholangiocarcinoma cells via inhibition of autophagy

Tumor protein p53 has been intensively studied as a major tumor suppressor. The activation of p53 is associated with various anti-neoplastic functions, including cell senescence, cell cycle arrest, apoptosis and inhibition of angiogenesis. However, the role of p53 in cancer cell chemosensitivity rem...

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Detalles Bibliográficos
Autores principales: Hu, Fei, Guo, Xian-Ling, Zhang, Shan-Shan, Zhao, Qiu-Dong, Li, Rong, Xu, Qing, Wei, Li-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530065/
https://www.ncbi.nlm.nih.gov/pubmed/28789429
http://dx.doi.org/10.3892/ol.2017.6449