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CXCL12/SDF-1α induces migration via SRC-mediated CXCR4-EGFR cross-talk in gastric cancer cells

Metastasis is the primary cause of mortality in patients with advanced gastric carcinoma, and multiple signaling pathways promote the development of this condition. Stromal cell-derived factor-1 (SDF-1α/CXCL12), the main ligand for CXC chemokine receptor-4 (CXCR4), serves an important role in gastri...

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Detalles Bibliográficos
Autores principales: Cheng, Yu, Qu, Jinglei, Che, Xiaofang, Xu, Ling, Song, Na, Ma, Yanju, Gong, Jing, Qu, Xiujuan, Liu, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530148/
https://www.ncbi.nlm.nih.gov/pubmed/28781651
http://dx.doi.org/10.3892/ol.2017.6389