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Synergistic effect of bladder cancer-specific oncolytic adenovirus in combination with chemotherapy

Gene therapy with adenoviral early region gene (E1A) may enhance the susceptibility of neoplastic cells to chemotherapy-induced cell death. Our previous study developed a urothelium-specific oncolytic serotype 5 adenovirus (Ad5) with the uroplakin II (UPII) promoter controlling E1A expression. The p...

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Detalles Bibliográficos
Autores principales: Li, Shuwen, Wang, Fang, Zhai, Zhenxing, Fu, Shengjun, Lu, Jianzhong, Zhang, Hongjuan, Guo, Hongyu, Hu, Xuemei, Li, Renju, Wang, Zhiping, Rodriguez, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530188/
https://www.ncbi.nlm.nih.gov/pubmed/28781650
http://dx.doi.org/10.3892/ol.2017.6416