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Efficacy and safety of sarilumab monotherapy versus adalimumab monotherapy for the treatment of patients with active rheumatoid arthritis (MONARCH): a randomised, double-blind, parallel-group phase III trial

OBJECTIVES: To compare efficacy and safety of sarilumab monotherapy with adalimumab monotherapy in patients with active rheumatoid arthritis (RA) who should not continue treatment with methotrexate (MTX) due to intolerance or inadequate response. METHODS: MONARCH was a randomised, active-controlled,...

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Detalles Bibliográficos
Autores principales: Burmester, Gerd R, Lin, Yong, Patel, Rahul, van Adelsberg, Janet, Mangan, Erin K, Graham, Neil M H, van Hoogstraten, Hubert, Bauer, Deborah, Ignacio Vargas, Juan, Lee, Eun Bong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530335/
https://www.ncbi.nlm.nih.gov/pubmed/27856432
http://dx.doi.org/10.1136/annrheumdis-2016-210310