Carbamylation of vimentin is inducible by smoking and represents an independent autoantigen in rheumatoid arthritis

OBJECTIVES: Smoking has been connected to citrullination of antigens and formation of anti-citrullinated peptide antibodies (ACPAs) in rheumatoid arthritis (RA). Since smoking can modify proteins by carbamylation (formation of homocitrulline), this study was conducted to investigate these effects on...

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Detalles Bibliográficos
Autores principales: Ospelt, Caroline, Bang, Holger, Feist, Eugen, Camici, Giovanni, Keller, Stephan, Detert, Jacqueline, Krämer, Anette, Gay, Steffen, Ghannam, Khetam, Burmester, Gerd R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Clinical and Epidemiological Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530349/
https://www.ncbi.nlm.nih.gov/pubmed/28183721
http://dx.doi.org/10.1136/annrheumdis-2016-210059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530349/
https://www.ncbi.nlm.nih.gov/pubmed/28183721
http://dx.doi.org/10.1136/annrheumdis-2016-210059

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