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Pathway-Based Kernel Boosting for the Analysis of Genome-Wide Association Studies

The analysis of genome-wide association studies (GWAS) benefits from the investigation of biologically meaningful gene sets, such as gene-interaction networks (pathways). We propose an extension to a successful kernel-based pathway analysis approach by integrating kernel functions into a powerful al...

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Detalles Bibliográficos
Autores principales: Friedrichs, Stefanie, Manitz, Juliane, Burger, Patricia, Amos, Christopher I., Risch, Angela, Chang-Claude, Jenny, Wichmann, Heinz-Erich, Kneib, Thomas, Bickeböller, Heike, Hofner, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530424/
https://www.ncbi.nlm.nih.gov/pubmed/28785300
http://dx.doi.org/10.1155/2017/6742763