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Pathway-Based Kernel Boosting for the Analysis of Genome-Wide Association Studies
The analysis of genome-wide association studies (GWAS) benefits from the investigation of biologically meaningful gene sets, such as gene-interaction networks (pathways). We propose an extension to a successful kernel-based pathway analysis approach by integrating kernel functions into a powerful al...
Autores principales: | Friedrichs, Stefanie, Manitz, Juliane, Burger, Patricia, Amos, Christopher I., Risch, Angela, Chang-Claude, Jenny, Wichmann, Heinz-Erich, Kneib, Thomas, Bickeböller, Heike, Hofner, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530424/ https://www.ncbi.nlm.nih.gov/pubmed/28785300 http://dx.doi.org/10.1155/2017/6742763 |
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