Expression of the NRF2 Target Gene NQO1 Is Enhanced in Mononuclear Cells in Human Chronic Kidney Disease

Reduced nuclear factor erythroid 2-related factor 2 (NRF2) pathway activity was reported in models of chronic kidney disease (CKD). Pharmacological activation of NRF2 is supposed to improve renal function, but data concerning the NRF2 activity in human CKD are lacking. We investigated the NRF2 targe...

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Detalles Bibliográficos
Autores principales: Shen, Jianlin, Rasmussen, Marianne, Dong, Qi-Rong, Tepel, Martin, Scholze, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530440/
https://www.ncbi.nlm.nih.gov/pubmed/28785379
http://dx.doi.org/10.1155/2017/9091879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530440/
https://www.ncbi.nlm.nih.gov/pubmed/28785379
http://dx.doi.org/10.1155/2017/9091879

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