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Vitamin D receptor expression and associated gene signature in tumour stromal fibroblasts predict clinical outcome in colorectal cancer

OBJECTIVE: Colorectal cancer (CRC) is a major health concern. Vitamin D deficiency is associated with high CRC incidence and mortality, suggesting a protective effect of vitamin D against this disease. Given the strong influence of tumour stroma on cancer progression, we investigated the potential e...

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Detalles Bibliográficos
Autores principales: Ferrer-Mayorga, Gemma, Gómez-López, Gonzalo, Barbáchano, Antonio, Fernández-Barral, Asunción, Peña, Cristina, Pisano, David G, Cantero, Ramón, Rojo, Federico, Muñoz, Alberto, Larriba, María Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530491/
https://www.ncbi.nlm.nih.gov/pubmed/27053631
http://dx.doi.org/10.1136/gutjnl-2015-310977