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MEG2 is regulated by miR-181a-5p and functions as a tumour suppressor gene to suppress the proliferation and migration of gastric cancer cells

BACKGROUND: Protein-tyrosine phosphatase MEG2 (MEG2) is a classic tyrosine-specific protein tyrosine phosphatase (PTP). It has been reported that MEG2 participates in the carcinogenesis of the breast and liver. However, functions of MEG2 in gastric cancer remain poorly understood. METHODS: We examin...

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Detalles Bibliográficos
Autores principales: Liu, Zhijian, Sun, Feng, Hong, Yeting, Liu, Yanqing, Fen, Min, Yin, Kai, Ge, Xiaolong, Wang, Feng, Chen, Xi, Guan, Wenxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530520/
https://www.ncbi.nlm.nih.gov/pubmed/28747184
http://dx.doi.org/10.1186/s12943-017-0695-7