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Development of an accumulation assay and evaluation of the effects of efflux pump inhibitors on the retention of chlorhexidine digluconate in Pseudomonas aeruginosa and Staphylococcus aureus

BACKGROUND: Chlorhexidine digluconate (CHG) is used as a disinfectant. The emergence of pathogens resistant to the biocide raises health concern. Information on specific efflux mechanisms utilised by bacteria to confer reduced susceptibility to the biocide, may be used to develop ways of preventing...

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Detalles Bibliográficos
Autores principales: Mombeshora, Molly, Mukanganyama, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530522/
https://www.ncbi.nlm.nih.gov/pubmed/28747232
http://dx.doi.org/10.1186/s13104-017-2637-2