Prolonged Expression of an Anti-HIV-1 gp120 Minibody to the Female Rhesus Macaque Lower Genital Tract by AAV Gene Transfer

Topical microbicides are a leading strategy for prevention of HIV mucosal infection to women, however, numerous pharmacokinetic limitations associated with coitally-related dosing strategy have contributed to their limited success. Here we test the hypothesis that adeno-associated virus (AAV) mediat...

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Detalles Bibliográficos
Autores principales: Abdel-Motal, Ussama M., Harbison, Carole, Han, Thomas, Pudney, Jeffrey, Anderson, Deborah J., Zhu, Quan, Westmoreland, Susan, Marasco, Wayne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530589/
https://www.ncbi.nlm.nih.gov/pubmed/24965083
http://dx.doi.org/10.1038/gt.2014.56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530589/
https://www.ncbi.nlm.nih.gov/pubmed/24965083
http://dx.doi.org/10.1038/gt.2014.56

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