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Prolonged Expression of an Anti-HIV-1 gp120 Minibody to the Female Rhesus Macaque Lower Genital Tract by AAV Gene Transfer
Topical microbicides are a leading strategy for prevention of HIV mucosal infection to women, however, numerous pharmacokinetic limitations associated with coitally-related dosing strategy have contributed to their limited success. Here we test the hypothesis that adeno-associated virus (AAV) mediat...
Autores principales: | Abdel-Motal, Ussama M., Harbison, Carole, Han, Thomas, Pudney, Jeffrey, Anderson, Deborah J., Zhu, Quan, Westmoreland, Susan, Marasco, Wayne A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530589/ https://www.ncbi.nlm.nih.gov/pubmed/24965083 http://dx.doi.org/10.1038/gt.2014.56 |
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