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Synthesis of oligonucleotides on a soluble support

Oligonucleotides are usually prepared in lab scale on a solid support with the aid of a fully automated synthesizer. Scaling up of the equipment has allowed industrial synthesis up to kilogram scale. In spite of this, solution-phase synthesis has received continuous interest, on one hand as a techni...

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Detalles Bibliográficos
Autor principal: Lönnberg, Harri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530625/
https://www.ncbi.nlm.nih.gov/pubmed/28781703
http://dx.doi.org/10.3762/bjoc.13.134