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Synthesis of oligonucleotides on a soluble support
Oligonucleotides are usually prepared in lab scale on a solid support with the aid of a fully automated synthesizer. Scaling up of the equipment has allowed industrial synthesis up to kilogram scale. In spite of this, solution-phase synthesis has received continuous interest, on one hand as a techni...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Beilstein-Institut
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530625/ https://www.ncbi.nlm.nih.gov/pubmed/28781703 http://dx.doi.org/10.3762/bjoc.13.134 |