Construction of highly enantioenriched spirocyclopentaneoxindoles containing four consecutive stereocenters via thiourea-catalyzed asymmetric Michael–Henry cascade reactions

The thiourea-catalyzed asymmetric synthesis of highly enantioenriched spirocyclopentaneoxindoles containing chiral amide functional groups using simple 3-substituted oxindoles and nitrovinylacetamide as starting materials was achieved successfully. This protocol features operational simplicity, high...

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Detalles Bibliográficos
Autores principales: Du, Yonglei, Li, Jian, Chen, Kerong, Wu, Chenglin, Zhou, Yu, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530720/
https://www.ncbi.nlm.nih.gov/pubmed/28781700
http://dx.doi.org/10.3762/bjoc.13.131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530720/
https://www.ncbi.nlm.nih.gov/pubmed/28781700
http://dx.doi.org/10.3762/bjoc.13.131

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