Hypermethylation of secreted frizzled-related proteins predicts poor prognosis in non-M3 acute myeloid leukemia

OBJECTIVE: Secreted frizzled-related proteins (SFRPs) as Wnt signaling antagonists have been found to be dysregulated by promoter hypermethylation in several cancers including acute myeloid leukemia (AML). This study aimed to investigate the methylated status of SFRPs promoter region and its clinica...

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Detalles Bibliográficos
Autores principales: Guo, Hong, Zhang, Ting-juan, Wen, Xiang-mei, Zhou, Jing-dong, Ma, Ji-chun, An, Cui, Zhang, Wei, Xu, Zi-jun, Lin, Jiang, Qian, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530859/
https://www.ncbi.nlm.nih.gov/pubmed/28790854
http://dx.doi.org/10.2147/OTT.S136502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530859/
https://www.ncbi.nlm.nih.gov/pubmed/28790854
http://dx.doi.org/10.2147/OTT.S136502

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