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Hypermethylation of secreted frizzled-related proteins predicts poor prognosis in non-M3 acute myeloid leukemia
OBJECTIVE: Secreted frizzled-related proteins (SFRPs) as Wnt signaling antagonists have been found to be dysregulated by promoter hypermethylation in several cancers including acute myeloid leukemia (AML). This study aimed to investigate the methylated status of SFRPs promoter region and its clinica...
Autores principales: | Guo, Hong, Zhang, Ting-juan, Wen, Xiang-mei, Zhou, Jing-dong, Ma, Ji-chun, An, Cui, Zhang, Wei, Xu, Zi-jun, Lin, Jiang, Qian, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530859/ https://www.ncbi.nlm.nih.gov/pubmed/28790854 http://dx.doi.org/10.2147/OTT.S136502 |
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