Epithelial requirement for in vitro proliferation and xenograft growth and metastasis of MDA-MB-468 human breast cancer cells: oncogenic rather than tumor-suppressive role of E-cadherin

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) is associated with downregulated E-cadherin and frequently with decreased proliferation. Proliferation may be restored in secondary metastases by mesenchymal-to-epithelial transition (MET). We tested whether E-cadherin maintains epithelial proli...

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Detalles Bibliográficos
Autores principales: Hugo, H. J., Gunasinghe, N. P. A. D., Hollier, B. G., Tanaka, T., Blick, T., Toh, A., Hill, P., Gilles, C., Waltham, M., Thompson, E. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530912/
https://www.ncbi.nlm.nih.gov/pubmed/28750639
http://dx.doi.org/10.1186/s13058-017-0880-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530912/
https://www.ncbi.nlm.nih.gov/pubmed/28750639
http://dx.doi.org/10.1186/s13058-017-0880-z

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