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Assessing the model transferability for prediction of transcription factor binding sites based on chromatin accessibility

BACKGROUND: Computational prediction of transcription factor (TF) binding sites in different cell types is challenging. Recent technology development allows us to determine the genome-wide chromatin accessibility in various cellular and developmental contexts. The chromatin accessibility profiles pr...

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Detalles Bibliográficos
Autores principales: Liu, Sheng, Zibetti, Cristina, Wan, Jun, Wang, Guohua, Blackshaw, Seth, Qian, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530957/
https://www.ncbi.nlm.nih.gov/pubmed/28750606
http://dx.doi.org/10.1186/s12859-017-1769-7