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Drug-induced amino acid deprivation as strategy for cancer therapy

Cancer is caused by uncontrollable growth of neoplastic cells, leading to invasion of adjacent and distant tissues resulting in death. Cancer cells have specific nutrient(s) auxotrophy and have a much higher nutrient demand compared to normal tissues. Therefore, different metabolic inhibitors or nut...

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Detalles Bibliográficos
Autores principales: Fung, Marcus Kwong Lam, Chan, Godfrey Chi-Fung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530962/
https://www.ncbi.nlm.nih.gov/pubmed/28750681
http://dx.doi.org/10.1186/s13045-017-0509-9