Carborane-based design of a potent vitamin D receptor agonist

The vitamin D nuclear receptor (VDR) is a potential target for cancer therapy. It is expressed in many tumors and its ligand shows anticancer actions. To combine these properties with the application of boron neutron capture therapy (BNCT), we design and synthesize a potent VDR agonist based on the...

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Detalles Bibliográficos
Autores principales: Otero, Rocio, Seoane, Samuel, Sigüeiro, Rita, Belorusova, Anna Y., Maestro, Miguel A., Pérez-Fernández, Roman, Rochel, Natacha, Mouriño, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531031/
https://www.ncbi.nlm.nih.gov/pubmed/28808527
http://dx.doi.org/10.1039/c5sc03084f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531031/
https://www.ncbi.nlm.nih.gov/pubmed/28808527
http://dx.doi.org/10.1039/c5sc03084f

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